Lakeland Regional Medical Center

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Lakeland Regional Cancer Center
Lakeland Regional Cancer Center
Lakeland Regional Cancer Center

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Clinical Trial # 178-CL-101:  Overactive bladder

  • Solifenacin/Mirabegron Placebo combinations (6 arms) for patients with an overactive bladder. 
  •  Patients must have one grade 3 or 4  episode in a 7 day period,  be able to complete quality of life questionnaires, have urinary frequency or urgency with incontinence for greater than 3 months, frequency of at least 8 times during a 24 hour period for 7 days and  have 3 incontinence episodes  in a 7 day period.
  • Exclusions include but are not limited to: Significant bladder outflow obstruction, significant stress incontinence, neurological causes,such as a neurogenic bladder,  intermittent self catherizations, have had intravesical treatment with the past 12 months or have severe hypertension or liver impairment.

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